Saxenda

What is Saxenda?

Saxenda is an injectable prescription medication approved by Singapore's Health Sciences Authority (HSA) and the US FDA for safe, effective, and long-term weight management. It contains an active ingredient called liraglutide, a GLP-1 (glucagon-like peptide-1) receptor agonist, which helps control your appetite and reduce calorie intake.

Initially developed as a treatment for managing diabetes, doctors discovered that liraglutide also effectively aids in sustainable weight loss. It does this by mimicking the natural GLP-1 hormone, sending signals to your brain to help you feel fuller for longer periods and thus naturally reducing hunger, cravings, and overall food consumption.

Unlike short-term diet trends, extreme calorie restriction, or over-the-counter appetite suppressants, Saxenda is scientifically proven to deliver safe, gradual, and lasting weight loss results, provided it is used in conjunction with balanced nutrition and regular exercise.

With consistent use, many individuals in Singapore have successfully incorporated Saxenda into their long-term health routines, achieving sustainable weight reduction and overall improvement in their metabolic health.

How Does Saxenda Work?

  • Appetite control. Saxenda mimics the GLP-1 hormone, signalling to the brain that you are full, reducing hunger and cravings.
  • Reduces caloric intake. Naturally lowers portion sizes and prevents overeating.
  • Slows digestion. Delays stomach emptying, making you feel fuller for longer.
  • Regulates blood sugar levels. Helps maintain stable glucose levels, reducing fat storage and promoting fat burn.
  • Sustainable weight loss. Encourages gradual and consistent weight reduction, avoiding extreme, rapid weight loss.

With continued use, Saxenda supports long-term weight maintenance by improving metabolic health and reducing obesity-related risks.

Who is Saxenda Suitable For?

Saxenda is recommended for:

  • Adults with a BMI of 30 or higher (obesity category).
  • Individuals with a BMI of 27 or higher with weight-related conditions, such as:
    • Type 2 diabetes
    • High blood pressure
    • High cholesterol
    • Sleep apnea
  • Those who have struggled to lose weight with diet and exercise alone.
  • Individuals looking for a non-surgical weight loss solution.

Saxenda is NOT suitable for:

  • Pregnant or breastfeeding women.
  • Individuals with a history of thyroid cancer or pancreatitis.
  • Those with severe gastrointestinal conditions.
  • People allergic to liraglutide or any components of the injection.

How Effective is Saxenda?

Saxenda in Singapore

Clinical trials have shown that Saxenda is highly effective for weight loss when combined with lifestyle modifications:

In a 56-week study:

  • 85% of participants lost weight while using Saxenda.
  • 3 out of 5 patients lost at least 5% of their body weight (equivalent to 5-10kg).
  • 1 in 3 lost more than 10% of their weight.
  • Significant reduction in waist circumference, improving metabolic health.

Most users experience visible weight loss within 8-12 weeks, with steady improvements over 6-12 months.

Saxenda Treatment Plan: Dosage & Administration

How to Use Saxenda?

Saxenda is a self-administered injection delivered once daily using a pre-filled pen.

Recommended Dosage Schedule:

Week Daily Dosage
Week 10.6mg per day
Week 21.2mg per day
Week 31.8mg per day
Week 42.4mg per day
Week 5 and beyondFull maintenance dose of 3.0mg per day

Injection Sites: 

Saxenda is injected into the abdomen, thigh, or upper arm.

Time of Day: 

Can be taken at any time, but should be consistent daily.

What Should You Do If You Missed A Dose?

If it’s been less than 12 hours, take the dose. If more than 12 hours have passed, skip the missed dose and continue as usual.

What Are The Benefits of Saxenda for Weight Loss?

  • Clinically proven weight loss: Helps reduce 5-15% of body weight when used consistently.
  • Regulates appetite and hunger cravings: Makes calorie reduction easier.
  • Improves metabolic health: Lowers blood sugar, cholesterol, and blood pressure.
  • Non-surgical and safe: A medical alternative to bariatric surgery.
  • Sustainable weight management: Supports long-term weight loss maintenance.

Saxenda Side Effects & Safety Considerations

Like any medication, Saxenda may cause mild to moderate side effects, particularly in the early stages of treatment.

Common Side Effects (Temporary & Manageable):

  • Nausea. The most common initial side effect, which usually improves over time.
  • Diarrhea or constipation. Can be managed with hydration and dietary adjustments.
  • Mild headaches and dizziness. Temporary as the body adjusts.
  • Injection site reactions. Redness, swelling, or irritation that resolves quickly.

Serious Side Effects (Rare – Seek Medical Advice):

  • Severe stomach pain, nausea, or vomiting. May indicate pancreatitis.
  • Gallbladder issues. Symptoms like sudden abdominal pain or jaundice.
  • Heart palpitations. Rapid or irregular heartbeat.

If any severe reactions occur, consult your doctor immediately.

Saxenda vs Other Weight Loss Medications

MedicationActive IngredientFrequencyUse CaseEffectiveness
SaxendaLiraglutideDaily injectionFDA-approved for weight lossModerate weight loss
OzempicSemaglutideWeekly injectionApproved for diabetes (off-label for weight loss)Higher weight loss observed
WeGovySemaglutideWeekly injectionFDA-approved for weight lossHigher weight loss observed

Key Differences:

  • Saxenda requires daily administration, while Ozempic and WeGovy are weekly injections.
  • WeGovy and Ozempic tend to show higher weight loss percentages in clinical studies.

What Is The Cost Of Saxenda In Singapore?

  • Saxenda Price Range: SGD $140 – $180 per pen
  • Doctor Consultation: $50 – $100 for an initial evaluation
  • Total Monthly Cost: $700 – $1,000, depending on dosage and clinic pricing

Saxenda is not covered under insurance, but some clinics offer package deals or installment plans.

Frequently Asked Questions (FAQs)

How quickly will I see results with Saxenda?

Most users notice weight loss within 4-8 weeks, with optimal results over 6-12 months.

Will I regain weight if I stop using Saxenda?

Without healthy lifestyle changes, weight regain is possible. A doctor-supervised transition plan helps maintain results.

Can I drink alcohol while taking Saxenda?

Alcohol may increase nausea and affect blood sugar levels, so moderation is recommended.

Is Saxenda painful to inject?

Most users report minimal discomfort, as the needle is ultra-thin.

Can I take Saxenda if I’m not obese but want to lose weight?

Saxenda is approved for overweight individuals with BMI 27+ who have weight-related health conditions.

Can pregnant or breastfeeding women use Saxenda?

No. Saxenda is not safe for pregnancy or breastfeeding.

Is Saxenda a long-term treatment?

Yes. Saxenda can be used long-term, provided there are no severe side effects.

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